CDC's official MMWR electronic copy of record is the MMWR in Adobe Acrobat portable document format (.pdf). The .pdf MMWR is identical in content to the paper copy of record. The MMWR text that follows is in ASCII text file format and has not been proofread. An adequate ASCII translation does not exist for each character possibly present in the .pdf file, and there may be other significant character translation errors. Also, the ASCII text that follows lacks the figures and tables of the electronic .pdf and paper format of MMWR. Therefore, CDC does not consider this ASCII text file to represent a copy of record of the MMWR. -------------------------------------------------------------- National Diabetes Awareness Month -- November 1995 November is National Diabetes Awareness Month. In the United States, approximately half of the 16 million persons with diabetes are believed to be aware that they have this condition. This year, efforts will emphasize increasing awareness among health professionals and the public about scientific findings that confirm the benefit of glycemic control and comprehensive strategies in preventing several complications of diabetes. Special materials are available from a consortium of federal agencies and private organizations (1). These materials include information about diabetes and its preventable complications (i.e., amputations, blindness, cardiovascular disease, and renal disease). Additional information about diabetes is available from diabetes-control programs in state and territorial health departments, and a Diabetes Home Page is now available through the CDC home page on the Internet World Wide Web (http://www.cdc.gov/nccdphp/ddt/ddthome.htm). Reference 1. CDC. Availability of information on diabetes awareness. MMWR 1995;44:821-2. Cardiovascular Disease Risk Factors and Related Preventive Health Practices Among Adults With and Without Diabetes -- Utah, 1988-1993 The risk for cardiovascular disease (CVD) among persons with diabetes is two to three times higher than among persons without diabetes, and CVD accounts for 48% of all deaths among persons with diabetes (1,2). To estimate the prevalence of CVD risk factors among and related preventive health practices of the adult population with diabetes in Utah, the Utah Diabetes Control Program (UDCP) previously had relied primarily on data from national surveys. To guide in planning and decision-making about future activities of the UDCP and to assess CVD-related behaviors and health practices among persons with diabetes, UDCP analyzed data from Utah's Behavioral Risk Factor Surveillance System (BRFSS) for 1988-1993. This report presents the findings of this analysis. Data were available for 10,388 adults who participated in the Utah BRFSS during 1988-1993. The BRFSS is a state-specific, population-based, random-digit-dialed telephone survey of the civilian, noninstitutionalized population aged greater than or equal to 18 years. The analysis examined sociodemographic characteristics, CVD risk factors, and related preventive health practices of all BRFSS respondents. SUDAAN was used to weight the results to reflect the age and sex distributions of the Utah population aged greater than or equal to 18 years and to control for potential confounding by age and sex using logistic regression (3). Of the 10,388 respondents, 405 (3.4% [95% confidence interval (CI)=3.0%-3.8%]) reported having been told by a physician they have diabetes. The unadjusted results indicated that persons with diabetes were more likely than persons without diabetes to be older and female, to have attained a lower level of education, to be retired, and to have lower annual incomes (Table 1). Among persons with diabetes, risk factors for CVD were highly prevalent (Table 2): 50% reported having been told by a health-care professional they have high blood pressure, and 11% reported current smoking*. After controlling for potential confounding by age and sex, persons with diabetes were approximately 2.5 times more likely than persons without diabetes to report having high blood pressure (odds ratio [OR]=2.7; 95% CI=2.1-3.4) and to be obese** (OR=2.5; 95% CI=2.0-3.2) and somewhat more likely to report a sedentary lifestyle*** (OR=1.3; 95% CI=1.0-1.7). Persons with diabetes were more likely than persons without diabetes to report having engaged in health practices to prevent CVD (Table 2), including having had a routine examination (86% versus 62%), having had their blood cholesterol checked during the preceding year (68% versus 39%), and trying to lose weight (41% versus 32%). However, of persons who reported trying to lose weight, those with diabetes were less likely to report using exercise, either alone or in conjunction with diet, than persons without diabetes (45% versus 71%). Differences in the prevalence of preventive health behaviors persisted after controlling for age and sex: routine examination (OR=2.6; 95% CI=1.8-3.8), blood cholesterol check (OR=2.0; 95% CI=1.5-2.5), trying to lose weight (OR=1.5; 95% CI=1.1-2.1). Reported by: B Larsen, MPH, M Friedrichs, MS, Diabetes Control Program, R Giles, Bur of Health Promotion, Div of Community and Family Health Svcs; Bur of Surveillance and Analysis, Office of Public Health Data, Utah Dept of Health. Epidemiology and Statistics Br, Div of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, CDC. Editorial Note: In Utah, characteristics of persons with and without diabetes are similar to national patterns: among persons with diabetes, higher proportions are older, have lower incomes, and are less educated (4). Based on these patterns, UDCP is collaborating with the state Medicare program to address the need for providers caring for patients with diabetes to receive reimbursement for outpatient education and nutrition counseling, and to ensure access to diabetes education and counseling for Medicaid recipients. In addition, UDCP is adapting current diabetes educational materials for selected groups, including persons who attained low education levels. Although the prevalences of major CVD risk factors in the adult population of Utah were lower than national prevalences (5,6), the BRFSS findings documented substantially higher prevalences among persons with diabetes. Based on these findings, UDCP will initiate efforts to increase patient and community awareness about CVD risk factors by 1) educating community members through outreach activities; 2) training local health department staff to emphasize the importance of diabetes education and the reduction of CVD risk factors (e.g., smoking and sedentary lifestyle); and 3) implementing a statewide media campaign with the Utah Diabetes Awareness Partnership about CVD risk factors. The BRFSS findings also will be used to increase awareness and improve care practices among health-care providers through 1) professional education seminars for primary-care physicians in rural areas, geriatric nurses working in home health, and mid-level practitioners; 2) development of office reminder systems to improve the quality of care in the primary-care setting, and 3) collaboration with the state Medicaid program to develop statewide standards of care for persons with diabetes. Beginning in 1994, CDC-funded cooperative agreements facilitated the restructuring of state diabetes-control programs to emphasize quality of care and monitoring of behavioral risk factors and preventive health practices (7). Based on the findings in this report, the Utah Department of Health will emphasize development of strategies to increase awareness about CVD risk factors and related preventive health behaviors and to improve medical care for persons with diabetes. In 1994, UDCP expanded surveillance efforts to include the use of the new BRFSS diabetes module recently developed by CDC to collect additional information from persons with diabetes about diabetes education, glycemic control, the frequency of screening for diabetic complications, and impaired visual acuity. These data are not available from other state-specific data sources and will enable the UDCP to evaluate the impact of efforts to improve the health status of persons with diabetes. References 1. CDC. The prevention and treatment of complications of diabetes mellitus: a guide for primary care practitioners. Atlanta, Georgia: US Department of Health and Human Services, Public Health Service, CDC, 1991. 2. CDC. Diabetes surveillance, 1993. Atlanta, Georgia: US Department of Health and Human Services, Public Health Service, CDC, 1993. 3. Shah BV. SUDAAN. Professional software for survey data analysis for multistage sample designs. Research Triangle Park, North Carolina: Research Triangle Institute, 1992. 4. Cowie CC, Eberhardt MS. Sociodemographic characteristics of persons with diabetes. In: National Diabetes Data Group, National Institutes of Health. Diabetes in America. 2nd ed. Bethesda, Maryland: US Department of Health and Human Services, Public Health Service, National Institutes of Health, 1995:85-116; DHHS publication no. (NIH)95-1468. 5. Siegel PZ, Brackbill RM, Frazier EL, et al. Behavioral risk factor surveillance, 1986-1990. In: CDC Surveillance Summaries (December). MMWR 1991;40(no. SS-4). 6. CDC. Prevalence of adults with no known major risk factors for coronary heart disease--Behavioral Risk Factor Surveillance System, 1992. MMWR 1994;43:61-63,69. 7. CDC. State-based programs to reduce the burden of diabetes: guidelines for program design, implementation, and evaluation. Atlanta, Georgia: US Department of Health and Human Services, Public Health Service, CDC, 1994. * Persons who smoked at least 100 cigarettes during their lifetime and who reported smoking at the time of the interview. ** Body mass index (kg/m2) greater than or equal to 27.8 for men and greater than or equal to 27.3 for women. *** Fewer than three 20-minute sessions of leisure-time physical activity per week. Progress Toward Poliomyelitis Eradication -- Eastern Mediterranean Region, 1988-1994 In 1988, the Regional Committee of the Eastern Mediterranean Region (EMR) of the World Health Organization* (WHO) adopted a resolution to eradicate poliomyelitis from the region by the year 2000 (1). Since this goal was established, substantial progress toward polio eradication has been achieved using three major strategies: 1) achieving and maintaining high coverage with at least three doses of oral poliovirus vaccine (OPV3); 2) implementing supplementary vaccination activities, including National Immunization Days (NIDs)**, to rapidly interrupt poliovirus transmission; and 3) developing sensitive systems of epidemiologic and laboratory surveillance, including use of the standard WHO case definition (2).*** This report summarizes progress toward polio eradication in EMR countries from 1988 through 1994 and is based on reports received through August 1, 1995. Incidence of Polio From 1988 through 1994, the number of confirmed polio cases reported in the region decreased 57%, from 2342 to 1015 (Figure 1). The sharp decline in reported cases from 1993 (2451 cases) to 1994 (1015 cases) especially reflected improved control of polio in Pakistan and Sudan, both of which experienced large outbreaks in 1993. Both countries conducted NIDs for the first time in 1994. Despite the substantial decrease in the number of cases reported from 1993 to 1994, Pakistan continues to report more cases than any other country in the region; the 527 cases reported in 1994 represent 52% of the regional total. During 1994, nine other countries reported polio cases, including Yemen (173 [17%]), Egypt (120 [10%]), Iran (93 [9%]), Iraq (63 [6%]), Sudan (25 [2%]), Saudi Arabia (six [0.5%]), Jordan (four [0.3%]), and Lebanon and Syria (one each [0.1%]). Eleven countries reported no cases. Five countries (Cyprus, Kuwait, Libya, Morocco, and Qatar) have reported no cases for at least 3 years. Vaccination Coverage From 1990 through 1993, routine coverage with OPV3 among children aged less than 1 year in EMR was greater than or equal to 80%; coverage decreased in 1994 to 78% (Figure 1). Of 20 countries reporting OPV3 coverage in 1994, a total of 16 reported coverage greater than 80%. Of these, 12 reported OPV3 coverage greater than 90%. The decrease in coverage in 1994 primarily reflected declining coverage in four countries (Djibouti, Pakistan, Sudan, and Yemen). In conjunction with declining routine vaccination coverage, Pakistan experienced an outbreak of paralytic polio in the second and third quarters of 1995 in its most populous province (Punjab). NIDs were conducted in two countries (Egypt and Syria) in 1993 and in five countries (Egypt, Iran, Pakistan, Sudan, and Syria) in 1994. By the end of 1995, a total of 19 (82%) countries, representing 93% of the estimated population in the region, will have conducted NIDs (Figure 2). Cyprus, Djibouti, Somalia, and Yemen will not conduct NIDs in 1995. Surveillance By 1992, a total of 21 of the 23 countries in EMR had developed surveillance for polio; surveillance could not be established in Afghanistan and Somalia because of civil conflict. By 1994, a total of 19 countries had established systems for reporting and monitoring the occurrence of acute flaccid paralysis (AFP), compared with six countries in 1992. Four countries (Afghanistan, Pakistan, Somalia, and Yemen) are not reporting cases of AFP. By 1994, AFP or polio cases were being investigated clinically and epidemiologically in 21 countries, compared with eight in 1992. An important indicator of the sensitivity of surveillance that has been consistent in many countries throughout the world is the rate of nonpolio AFP among children aged less than 15 years (greater than or equal to 1 case per 100,000); by 1994, five EMR countries had achieved this rate. Laboratory Support By 1994, laboratory surveillance for polioviruses had been initiated in 14 countries, compared with six in 1992. In 1994, the EMR laboratory network was involved in the investigation of 717 AFP cases. Of these, two stool specimens were available for 495 (69%). Of 422 cases with onset and collection data available, 354 (84%) had stool specimens collected within 14 days of onset of paralysis. Reported by: Regional Office for the Eastern Mediterranean Region, Alexandria, Egypt; Global Program for Vaccines and Immunization, World Health Organization, Geneva. Respiratory and Enterovirus Br, National Center for Infectious Diseases; Polio Eradication Activity, National Immunization Program, CDC. Editorial Note: The findings in this report document substantial progress toward polio eradication in EMR during 1988-1994. In addition to providing member countries with technical support to implement global polio eradication strategies, the EMR has initiated three major regional initiatives to accelerate polio eradication. First, during 1993-1994, WHO collaborated with Rotary International and the United Nations Children's Fund (UNICEF) and used teams of national and international laboratory and epidemiology experts to conduct rapid surveillance assessments in 19 countries. Second, WHO coordinated efforts (including NIDs) to detect and prevent cases in three geographically contiguous and epidemiologically similar countries (the Mahgreb Union in Northern Africa; the Arab Gulf states; and the Middle Eastern and Asian states of Jordan, Lebanon, Palestine, Syria, Afghanistan, Iran, Iraq, and Pakistan) to foster the emergence of polio-free zones within the region. Third, a monthly newsletter ("Poliofax") is sent to all ministries of health in the region to provide feedback and to encourage complete and timely disease reporting. Despite progress toward polio eradication, some barriers persist and underscore the need to 1) increase vaccination levels in unvaccinated subpopulations; 2) maintain high routine vaccination coverage in all member countries; 3) translate political commitment into action, including the provision of sufficient funds for the purchase of oral polio vaccine (both for routine and supplementary vaccination) by governments of all member countries; 4) encourage all member countries to establish polio eradication as a priority activity, including the initiation of AFP surveillance and implementation of NIDs; 5) overcome the impediments to the regional polio eradication initiative as the result of war and civil strife in some countries; and 6) strengthen the timely exchange of information among countries and with WHO, UNICEF, Rotary International, and other partner organizations to enable coordination and enhanced support of regional polio eradication activities. References 1. Regional Committee for the Eastern Mediterranean Region, World Health Organization. Poliomyelitis eradication in the Eastern Mediterranean Region. Alexandria, Egypt: World Health Organization, 1988. (Resolution EM/RC35/R.14). 2. Hull HF, Ward NA, Hull BP, Milstien JB, de Quadros C. Paralytic poliomyelitis: seasoned strategies, disappearing disease. Lancet 1994;343:1331-7. * Member countries are Djibouti, Egypt, Libya, Morocco, Somalia, Sudan, and Tunisia in northern and eastern Africa; the Arab Gulf states of Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, United Arab Emirates, and Yemen; Iraq, Jordan, Lebanon, Syria, and the Palestinian people in the Middle East; Afghanistan, Iran, and Pakistan in Asia; and Cyprus. ** Mass campaigns over a short period (days to weeks) in which two doses of OPV are administered to all children in the target age group (usually age less than 5 years) regardless of prior vaccination history, with an interval of 4-6 weeks between doses. *** A confirmed case of polio is defined as acute flaccid paralysis and at least one of the following: 1) laboratory-confirmed wild poliovirus infection, 2) residual paralysis at 60 days, 3) death, or 4) no follow-up investigation at 60 days. Hospitalization for Epilepsy -- United States, 1988-1992 Epilepsy is a chronic neurologic condition manifested by repeated unprovoked seizures that affects approximately 1% of the U.S. population (1). Although effective treatment can prevent seizures in most persons with epilepsy, some persons have frequent seizures, which can lead to brain damage, disability, and diminished quality of life (2,3). To assist in characterizing the public health impact of epilepsy in the United States, CDC analyzed data from the National Hospital Discharge Survey (NHDS) for 1988-1992 to estimate the number of hospitalizations for which epilepsy was the first-listed diagnosis. The NHDS is conducted annually and collects data from a sample of inpatient records obtained from a nationally representative sample of nonfederal general and short-stay specialty hospitals in the United States (4). Hospitalizations for which the first-listed diagnosis was epilepsy were selected by using the International Classification of Diseases, Ninth Revision, Clinical Modification, codes 345.0-345.9. Age-specific and age-adjusted rates were estimated for the civilian population; the direct method was used to age-adjust the estimates to the 1980 U.S. resident population. Because of differences in the racial designation of the denominator population in different years, race-specific rates for the total period could be estimated for whites only and for all other groups combined. Hospitalizations for persons with race not stated were included with whites. To increase the stability of the estimates, data for all 5 survey years were combined. SUDAAN was used to calculate the estimates and standard errors. From 1988 through 1992, epilepsy was the first-listed diagnosis for an estimated 466,000 hospitalizations; the age-adjusted hospitalization rate was 37 hospitalizations per 100,000 persons (Table 1). The age-specific rate per 100,000 persons varied by age group and was highest for persons aged greater than or equal to 65 years (68 per 100,000) and lowest for persons aged 15-64 years (30). The age-adjusted hospitalization rate was higher for males (40) than females (34); however, age-specific rates for males and females were similar (Table 1). The age-adjusted hospitalization rate was higher in the Northeast (49) than in the South (37), North Central (35), and West (27).* Age-adjusted rates were substantially lower for whites (35) than for all other racial groups combined (51). Age-specific rates were similar for the youngest age group; however, compared with whites, rates were higher in other age groups for the other racial groups combined (Figure 1). The ratio of rates increased directly by age group--0.9 among persons aged less than 15 years, 1.6 among those aged 15-64 years, and 1.8 among those aged greater than or equal to 65 years. Reported by: Statistics Br, Div of Chronic Disease Control and Community Intervention, National Center for Chronic Disease Prevention and Health Promotion, CDC. Editorial Note: Hospitalizations for epilepsy represent a potentially preventable complication of this condition. The findings in this report indicate that, during 1988-1992, approximately 93,000 hospitalizations each year were attributed to epilepsy. These rates are similar to those reported for 1973-1976 (5) and to rates based on studies employing rigorous ascertainment of cases (6). Comparing these results with the estimated prevalence of self-reported epilepsy (7), approximately 8% of persons with epilepsy are hospitalized each year. The proportion of persons hospitalized is similar for men and women but varies considerably with age; an estimated one fourth of persons with epilepsy aged greater than or equal to 65 years are hospitalized each year with epilepsy as the first-listed diagnosis. This may be attributable to either severity of epilepsy, its underlying causes in older age groups, or underreporting of epilepsy in this population segment. Although data characterizing the prevalence of epilepsy by racial/ethnic group are limited, the prevalence among whites, in general, has been reported to be lower than for blacks (7,8). In 1992, 20% of NHDS records lacked a designation of race (7). Because most of these persons were discharged from hospitals that historically reported most of their patients as white, these records were included with whites in this analysis, thus resulting in an overestimate of hospitalization rates for whites. Despite this bias, however, the hospitalization rate for whites was different when compared with all other racial groups combined. In this analysis, this disparity increased directly with age, possibly reflecting cumulative differences in disease severity or access to effective therapy. The findings in this report are subject to at least two limitations. First, the hospitalization data could not be linked to individuals. Persons with particularly refractory seizures may have been hospitalized multiple times during the study period. Second, epilepsy may be the underlying factor for hospitalizations attributed to other causes (e.g., trauma). Therefore, this analysis probably underestimated the total number of hospitalizations for epilepsy. Although hospitalization accounts for only a small proportion of the total medical and public health impact of epilepsy, rates of hospitalization for epilepsy are especially high in some age groups. In addition, hospitalizations attributable to epilepsy are preventable with effective outpatient management focusing on proper diagnosis, treatment, and patient compliance. Patients with epilepsy refractory to treatment in the primary-care setting or those experiencing difficulties in compliance or adverse effects of antiepileptic medication should be referred to appropriate specialty centers for the diagnosis and treatment of epilepsy (9). CDC is collaborating with representatives of professional and voluntary organizations to develop guidelines for consumers and health-care providers for the management and referral of persons with epilepsy in primary-care settings. November is National Epilepsy Month. Additional information about epilepsy and its treatment is available from the Epilepsy Foundation of America, telephone (800) 332-1000 or (301) 459-3700. References 1. Hauser WA, Hesdorffer DC. Epilepsy: frequency, causes, and consequences. New York: Epilepsy Foundation of America, 1990. 2. Annegers JF, Hauser WA, Elveback LR. Remission of seizures and relapse in patients with epilepsy. Epilepsia 1979;20:729-37. 3. Dodrill CB. Correlates of generalized tonic-clonic seizures with intellectual, neuropsychological, emotional, and social function in patients with epilepsy. Epilepsia 1986;27:399-411. 4. NCHS. National Hospital Discharge Survey: annual summary, 1992. Hyattsville, Maryland: US Department of Health and Human Services, Public Health Service, CDC, October 1994. (Vital and health statistics; series 13, no. 119). 5. Jerath BK, Kimbell BA. Hospitalization rates for epilepsy in the United States, 1973-1976. Epilepsia 1981;22:55-64. 6. Hauser WA, Kurland LT. The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967. Epilepsia 1975;16:1-66. 7. CDC. Prevalence of self-reported epilepsy--United States, 1986-1990. MMWR 1994;43;810-1,817-8. 8. Haerer AF, Anderson DW, Schoenberg BS. Prevalence and clinical features of epilepsy in a biracial United States population. Epilepsia 1986;27:66-75. 9. Lesser RP. The role of epilepsy centers in delivering care to patients with intractable epilepsy. Neurology 1994;44:1347-52. * Northeast=Connecticut, Maine, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont; North Central=Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin; South=Alabama, Arkansas, Delaware, District of Columbia, Florida, Georgia, Kentucky, Louisiana, Maryland, Mississippi, North Carolina, Oklahoma, South Carolina, Tennessee, Texas, Virginia, and West Virginia; West=Alaska, Arizona, California, Colorado, Hawaii, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, and Wyoming. Notice to Readers Availability of Information on Diabetes Awareness Three resources to promote diabetes awareness have recently been published and are available to the public. The 1995 National Diabetes Fact Sheet provides statistical information about the impact of diabetes in the United States. The fact sheet was a collaborative effort involving a consortium of federal agencies (CDC; the Health and Human Resource Services Administration; the Indian Health Service; the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health; and the Department of Veterans Affairs) and volunteer diabetes organizations (the American Association of Diabetes Educators, the American Diabetes Association, and the Juvenile Diabetes Foundation). The document is available free of charge through any of the agencies or national headquarters of the organizations participating in the consortium or on CDC's Diabetes Home Page on Internet (http://www.cdc.gov/nccdphp/ddt/ddthome.htm). To order the document from CDC, write to TISB, Mailstop K-13, Attention: DK, CDC, 4770 Buford Highway, N.E., Atlanta, GA 30341-3724. This consortium, as well as the Pedorthic Footwear Association (PFA) and the California College of Podiatric Medicine (CCPM), is collaborating on a foot-care awareness campaign to detect loss of protective foot sensation, which can lead to foot ulcers and eventually to amputations. Additional information about the campaign is available from any of the agencies or national headquarters of the organizations participating in the consortium, PFA, or CCPM. The National Diabetes Data Group, National Institutes of Health, has published Diabetes in America, 2nd Edition, a compilation and assessment of the scope and impact of diabetes in the United States (1). The book addresses the descriptive epidemiology of diabetes, complications of the disease, characteristics of therapy and medical care for diabetes, economic aspects, and diabetes in specific racial/ethnic populations. A substantial portion of the data is derived from CDC's National Center for Health Statistics surveys, including the National Health Interview Survey, National Health and Nutrition Examination Survey, National Hospital Discharge Survey, National Ambulatory Medical Care Survey, and the vital statistics system. The document is available for $20 (postage and handling charge) from the National Diabetes Information Clearinghouse, National Institute of Diabetes and Digestive and Kidney Diseases, One Information Way, Bethesda, MD, 20892-3560; telephone (301) 654-3327. References 1. National Diabetes Data Group, National Institutes of Health. Diabetes in America. 2nd ed. Bethesda, Maryland: US Department of Health and Human Services, Public Health Service, National Institutes of Health, 1995; DHHS publication no. (NIH)95-1468.